Epitope-Specific Anti-C1q Autoantibodies in Systemic Lupus Erythematosus

OBJECTIVE: In patients with systemic lupus erythematosus (SLE) complement C1q is frequently targeted by autoantibodies (anti-C1q), that correlate best with active renal disease. Anti-C1q bind to largely unknown epitopes on the collagen-like region (CLR) of this highly functional molecule. Here we ai...

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Detalles Bibliográficos
Autores principales: Kleer, Jessica S., Rabatscher, Pascal A., Weiss, Jessica, Leonardi, Joel, Vogt, Severin B., Kieninger-Gräfitsch, Andrea, Chizzolini, Carlo, Huynh-Do, Uyen, Ribi, Camillo, Trendelenburg, Marten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788646/
https://www.ncbi.nlm.nih.gov/pubmed/35087514
http://dx.doi.org/10.3389/fimmu.2021.761395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788646/
https://www.ncbi.nlm.nih.gov/pubmed/35087514
http://dx.doi.org/10.3389/fimmu.2021.761395

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