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Insights into the Antibacterial Mechanism of Action of Chelating Agents by Selective Deprivation of Iron, Manganese, and Zinc

Bacterial growth and proliferation can be restricted by limiting the availability of metal ions in their environment. Humans sequester iron, manganese, and zinc to help prevent infection by pathogens, a system termed nutritional immunity. Commercially used chelants have high binding affinities with...

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Detalles Bibliográficos
Autores principales: Paterson, Joy R., Beecroft, Marikka S., Mulla, Raminder S., Osman, Deenah, Reeder, Nancy L., Caserta, Justin A., Young, Tessa R., Pettigrew, Charles A., Davies, Gareth E., Williams, J. A. Gareth, Sharples, Gary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788741/
https://www.ncbi.nlm.nih.gov/pubmed/34788072
http://dx.doi.org/10.1128/AEM.01641-21