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Capillary Electrophoresis-Based Functional Genomics Screening to Discover Novel Archaeal DNA Modifying Enzymes

It has been predicted that 30 to 80% of archaeal genomes remain annotated as hypothetical proteins with no assigned gene function. Further, many archaeal organisms are difficult to grow or are unculturable. To overcome these technical and experimental hurdles, we developed a high-throughput function...

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Detalles Bibliográficos
Autores principales: Zatopek, Kelly M., Fossa, Samantha L., Bilotti, Katharina, Caffrey, Paul J., Chuzel, Léa, Gehring, Alexandra M., Lohman, Gregory J. S., Taron, Christopher H., Gardner, Andrew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788744/
https://www.ncbi.nlm.nih.gov/pubmed/34788065
http://dx.doi.org/10.1128/AEM.02137-21