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Capillary Electrophoresis-Based Functional Genomics Screening to Discover Novel Archaeal DNA Modifying Enzymes
It has been predicted that 30 to 80% of archaeal genomes remain annotated as hypothetical proteins with no assigned gene function. Further, many archaeal organisms are difficult to grow or are unculturable. To overcome these technical and experimental hurdles, we developed a high-throughput function...
Autores principales: | Zatopek, Kelly M., Fossa, Samantha L., Bilotti, Katharina, Caffrey, Paul J., Chuzel, Léa, Gehring, Alexandra M., Lohman, Gregory J. S., Taron, Christopher H., Gardner, Andrew F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788744/ https://www.ncbi.nlm.nih.gov/pubmed/34788065 http://dx.doi.org/10.1128/AEM.02137-21 |
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