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Whole-cell display of Pyrococcus horikoshii glutamate decarboxylase in Escherichia coli for high-titer extracellular gamma-aminobutyric acid production

We investigated the effect of cell-surface display of glutamate decarboxylase (GadB) on gamma-aminobutyric acid (GABA) production in recombinant Escherichia coli. We integrated GadB from the hyperthermophilic, anaerobic archaeon Pyrococcus horikoshii to the C-terminus of the E. coli outer membrane p...

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Detalles Bibliográficos
Autores principales: Somasundaram, Sivachandiran, Jeong, Jaehoon, Kumaravel, Ashokkumar, Hong, Soon Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788790/
https://www.ncbi.nlm.nih.gov/pubmed/34180519
http://dx.doi.org/10.1093/jimb/kuab039