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Whole-cell display of Pyrococcus horikoshii glutamate decarboxylase in Escherichia coli for high-titer extracellular gamma-aminobutyric acid production

We investigated the effect of cell-surface display of glutamate decarboxylase (GadB) on gamma-aminobutyric acid (GABA) production in recombinant Escherichia coli. We integrated GadB from the hyperthermophilic, anaerobic archaeon Pyrococcus horikoshii to the C-terminus of the E. coli outer membrane p...

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Detalles Bibliográficos
Autores principales:	Somasundaram, Sivachandiran, Jeong, Jaehoon, Kumaravel, Ashokkumar, Hong, Soon Ho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Metabolic Engineering and Synthetic Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788790/ https://www.ncbi.nlm.nih.gov/pubmed/34180519 http://dx.doi.org/10.1093/jimb/kuab039

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