Cargando…

2-Cl-IB-MECA regulates the proliferative and drug resistance pathways, and facilitates chemosensitivity in pancreatic and liver cancer cell lines

Specific A(3) adenosine receptor (A(3)AR) agonist, 2-chloro-N6-(3-iodobenzyl)-5′-N-methylcarboxamidoadenosine (2-Cl-IB-MECA), demonstrates anti-proliferative effects on various types of tumor. In the present study, the cytotoxicity of 2-Cl-IB-MECA was analyzed in a panel of tumor and non-tumor cell...

Descripción completa

Detalles Bibliográficos
Autores principales: Kotulova, Jana, Lonova, Katerina, Kubickova, Agata, Vrbkova, Jana, Kourilova, Pavla, Hajduch, Marian, Dzubak, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788926/
https://www.ncbi.nlm.nih.gov/pubmed/35039871
http://dx.doi.org/10.3892/ijmm.2022.5086