Cargando…

2-Cl-IB-MECA regulates the proliferative and drug resistance pathways, and facilitates chemosensitivity in pancreatic and liver cancer cell lines

Specific A(3) adenosine receptor (A(3)AR) agonist, 2-chloro-N6-(3-iodobenzyl)-5′-N-methylcarboxamidoadenosine (2-Cl-IB-MECA), demonstrates anti-proliferative effects on various types of tumor. In the present study, the cytotoxicity of 2-Cl-IB-MECA was analyzed in a panel of tumor and non-tumor cell...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kotulova, Jana, Lonova, Katerina, Kubickova, Agata, Vrbkova, Jana, Kourilova, Pavla, Hajduch, Marian, Dzubak, Petr
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788926/ https://www.ncbi.nlm.nih.gov/pubmed/35039871 http://dx.doi.org/10.3892/ijmm.2022.5086

Ejemplares similares

Current Adenosinergic Therapies: What Do Cancer Cells Stand to Gain and Lose?
por: Kotulová, Jana, et al.
Publicado: (2021)

Prevalence and genotype distribution of human papillomavirus in Czech non-vaccinated heterosexual couples
por: Jaworek, Hana, et al.
Publicado: (2021)

Impact of human papillomavirus infection on semen parameters and reproductive outcomes
por: Jaworek, Hana, et al.
Publicado: (2021)

Evaluation of Non-Invasive Gargle Lavage Sampling for the Detection of SARS-CoV-2 Using rRT-PCR or Antigen Assay
por: Bouska, Ondrej, et al.
Publicado: (2022)

Adoptive Immunotherapy with Cl-IB-MECA-Treated CD8+ T Cells Reduces Melanoma Growth in Mice
por: Montinaro, Antonella, et al.
Publicado: (2012)

Proteome Mapping of Cervical Mucus and Its Potential as a Source of Biomarkers in Female Tract Disorders
por: Oždian, Tomáš, et al.
Publicado: (2023)

Mass Spectrometry Amyloid Typing Is Reproducible across Multiple Organ Sites
por: Holub, Dusan, et al.
Publicado: (2019)

Prevalence of human papillomavirus infection in oocyte donors and women treated for infertility: An observational laboratory-based study()
por: Jaworek, Hana, et al.
Publicado: (2019)

Antiviral Activity of Selected Lamiaceae Essential Oils and Their Monoterpenes Against SARS-Cov-2
por: Ćavar Zeljković, Sanja, et al.
Publicado: (2022)

Head-To-Head Comparison of Biological Behavior of Biocompatible Polymers Poly(Ethylene Oxide), Poly(2-Ethyl-2-Oxazoline) and Poly[N-(2-Hydroxypropyl)Methacrylamide] as Coating Materials for Hydroxyapatite Nanoparticles in Animal Solid Tumor Model
por: Novy, Zbynek, et al.
Publicado: (2020)

Effect of Glucocorticosteroids in Diamond-Blackfan Anaemia: Maybe Not as Elusive as It Seems
por: Macečková, Zuzana, et al.
Publicado: (2022)

The effects of the adenosine A3 receptor agonist IB-MECA on sodium taurocholate-induced experimental acute pancreatitis
por: Prozorow-Krol, Beata, et al.
Publicado: (2013)

Cancer Cell Response to Anthracyclines Effects: Mysteries of the Hidden Proteins Associated with These Drugs
por: Tyleckova, Jirina, et al.
Publicado: (2012)

Effects of Ginger Phenylpropanoids and Quercetin on Nrf2-ARE Pathway in Human BJ Fibroblasts and HaCaT Keratinocytes
por: Schadich, Ermin, et al.
Publicado: (2016)

Differential Regulation of Methylation-Regulating Enzymes by Senescent Stromal Cells Drives Colorectal Cancer Cell Response to DNA-Demethylating Epi-Drugs
por: Agrawal, Khushboo, et al.
Publicado: (2018)

Amino-BODIPY as the ratiometric fluorescent sensor for monitoring drug release or “power supply” selector for molecular electronics
por: Porubský, Martin, et al.
Publicado: (2019)

Erratum to: The effects of the adenosine A3 receptor agonist IB-MECA on sodium taurocholate-induced experimental acute pancreatitis
por: Prozorow-Krol, Beata, et al.
Publicado: (2013)

Aurora kinase inhibitors: Progress towards the clinic
por: Kollareddy, Madhu, et al.
Publicado: (2012)

Cytotoxic conjugates of betulinic acid and substituted triazoles prepared by Huisgen Cycloaddition from 30-azidoderivatives
por: Sidova, Veronika, et al.
Publicado: (2017)

Sugar modified pyrimido[4,5-b]indole nucleosides: synthesis and antiviral activity
por: Konč, Juraj, et al.
Publicado: (2017)

MECA : mejora de la calidad de los antimicrobianos : recomendaciones SEQ /
Publicado: (2006)

Pyrido-Fused Deazapurine Bases: Synthesis and Glycosylation of 4-Substituted 9H-Pyrido[2′,3′:4,5]- and Pyrido[4′,3′:4,5]pyrrolo[2,3-d]pyrimidines
por: Veselovská, Lucia, et al.
Publicado: (2020)

Newly designed 11-gene panel reveals first case of hereditary amyloidosis captured by massive parallel sequencing
por: Chyra Kufova, Zuzana, et al.
Publicado: (2018)

Morphine Analgesia, Cannabinoid Receptor 2, and Opioid Growth Factor Receptor Cancer Tissue Expression Improve Survival after Pancreatic Cancer Surgery
por: Vecera, Lubomir, et al.
Publicado: (2023)

Identification of Meningioma Patients at High Risk of Tumor Recurrence Using MicroRNA Profiling
por: Slavik, Hanus, et al.
Publicado: (2020)

Cytotoxicity of Amino‐BODIPY Modulated via Conjugation with 2‐Phenyl‐3‐Hydroxy‐4(1H)‐Quinolinones
por: Porubský, Martin, et al.
Publicado: (2021)

Dentro de la Meca Inside Mecca /
Publicado: (2008)

Cannabinoid receptor 2 expression in early-stage non-small cell lung cancers identifies patients with good prognosis and longer survival
por: Vidlarova, Monika, et al.
Publicado: (2022)

Clinical and prognostic significance of detecting CEA, EGFR, LunX, c-met and EpCAM mRNA-positive cells in the peripheral blood, tumor-draining blood and bone marrow of non-small cell lung cancer patients
por: Rehulkova, Alona, et al.
Publicado: (2023)

Induction, regulation and roles of neural adhesion molecule L1CAM in cellular senescence
por: Mrazkova, Blanka, et al.
Publicado: (2018)

Acute Pneumonia Caused by Clinically Isolated Legionella pneumophila Sg 1, ST 62: Host Responses and Pathologies in Mice
por: Trousil, Jiří, et al.
Publicado: (2022)

The PI3K–NF-κB signal transduction pathway is involved in mediating the anti-inflammatory effect of IB-MECA in adjuvant-induced arthritis
por: Fishman, Pnina, et al.
Publicado: (2006)

The Histamine H(4) Receptor Participates in the Anti-Neuropathic Effect of the Adenosine A(3) Receptor Agonist IB-MECA: Role of CD4(+) T Cells
por: Micheli, Laura, et al.
Publicado: (2021)

Mixture Effects of Tryptophan Intestinal Microbial Metabolites on Aryl Hydrocarbon Receptor Activity
por: Vrzalová, Aneta, et al.
Publicado: (2022)

Transcriptomic Profiling Revealed Lnc-GOLGA6A-1 as a Novel Prognostic Biomarker of Meningioma Recurrence
por: Slavik, Hanus, et al.
Publicado: (2022)

Synthesis of Polycyclic Hetero-Fused 7-Deazapurine Heterocycles and Nucleosides through C–H Dibenzothiophenation and Negishi Coupling
por: Yang, Chao, et al.
Publicado: (2022)

De la Ceca a La Meca
por: Goytisolo, Juan 1931-
Publicado: (1997)

Cannabidiol‐induced activation of the metallothionein pathway impedes anticancer effects of disulfiram and its metabolite CuET
por: Buchtova, Tereza, et al.
Publicado: (2021)

Impact of the Stringent Stress Response on the Expression of Methicillin Resistance in Staphylococcaceae Strains Carrying mecA, mecA1 and mecC
por: Milheiriço, Catarina, et al.
Publicado: (2022)

The First Insight into Polyhydroxyalkanoates Accumulation in Multi-Extremophilic Rubrobacter xylanophilus and Rubrobacter spartanus
por: Kouřilová, Xenie, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_91r2ed2t5o43i5ebdbbibu5pkm