Cargando…

Dynamics of T cell receptor distributions following acute thymic atrophy and resumption

Naive human T cells are produced and developed in the thymus, which atrophies abruptly and severely in response to physical or psychological stress. To understand how an instance of stress affects the size and “diversity” of the peripheral naive T cell pool, we derive a mean-field autonomous ODE mod...

Descripción completa

Detalles Bibliográficos
Autores principales: Lewkiewicz, Stephanie M., Chuang, Yao-Li, Chou, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788929/
https://www.ncbi.nlm.nih.gov/pubmed/31731338
http://dx.doi.org/10.3934/mbe.2020002