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Dynamics of T cell receptor distributions following acute thymic atrophy and resumption
Naive human T cells are produced and developed in the thymus, which atrophies abruptly and severely in response to physical or psychological stress. To understand how an instance of stress affects the size and “diversity” of the peripheral naive T cell pool, we derive a mean-field autonomous ODE mod...
Autores principales: | Lewkiewicz, Stephanie M., Chuang, Yao-Li, Chou, Tom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788929/ https://www.ncbi.nlm.nih.gov/pubmed/31731338 http://dx.doi.org/10.3934/mbe.2020002 |
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