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Pharmacology of enflicoxib, a new coxib drug: Efficacy and dose determination by clinical and pharmacokinetic‐guided approach for the treatment of osteoarthritis in dogs based on an acute arthritis induction model

Enflicoxib is a newly developed NSAID of the coxib class. The optimal therapeutic dose to be confirmed in the field studies was established using a combination of pharmacokinetic (PK) modelling and pharmacodynamic (PD) studies. First, a PK study was performed to determine the plasmatic profile of en...

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Detalles Bibliográficos
Autores principales: Cendrós, Josep‐Maria, Salichs, Marta, Encina, Gregorio, Vela, Jose Miguel, Homedes, Josep M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788976/
https://www.ncbi.nlm.nih.gov/pubmed/34854245
http://dx.doi.org/10.1002/vms3.670