Angiotensin(1–7) activates MAS-1 and upregulates CFTR to promote insulin secretion in pancreatic β-cells: the association with type 2 diabetes

OBJECTIVE: The beneficial effect of angiotensin(1–7) (Ang(1–7)), via the activation of its receptor, MAS-1, has been noted in diabetes treatment; however, how Ang(1–7) or MAS-1 affects insulin secretion remains elusive and whether the endogenous level of Ang(1–7) or MAS-1 is altered in diabetic indi...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Xue-Lian, Zhao, Xinyi, Wu, Yong, Huang, Wen-qing, Chen, Jun-jiang, Hu, Peijie, Liu, Wei, Chen, Yi-Wen, Hao, Jin, Xie, Rong-Rong, Chan, Hsiao Chang, Ruan, Ye Chun, Chen, Hui, Guo, Jinghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789014/
https://www.ncbi.nlm.nih.gov/pubmed/34825893
http://dx.doi.org/10.1530/EC-21-0357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789014/
https://www.ncbi.nlm.nih.gov/pubmed/34825893
http://dx.doi.org/10.1530/EC-21-0357

Ejemplares similares