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Reduced pituitary size in subjects with mutations in the THRB gene and thyroid hormone resistance

BACKGROUND: Thyroid hormone action is mediated by two forms of thyroid hormone receptors (α, β) with differential tissue distribution. Thyroid hormone receptor β (TRβ) mutations lead to resistance to thyroid hormone action in tissues predominantly expressing the β form of the receptor (pituitary, li...

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Detalles Bibliográficos
Autores principales: Heldmann, Marcus, Chatterjee, Krishna, Moran, Carla, Rogge, Berenike, Steinhardt, Julia, Wagner-Altendorf, Tobias, Göttlich, Martin, Schacht, Hannes, Schramm, Peter, Brabant, Georg, Münte, Thomas F, Cirkel, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789019/
https://www.ncbi.nlm.nih.gov/pubmed/34860176
http://dx.doi.org/10.1530/EC-21-0473