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The interaction between the Spt6-tSH2 domain and Rpb1 affects multiple functions of RNA Polymerase II
The conserved transcription elongation factor Spt6 makes several contacts with the RNA Polymerase II (RNAPII) complex, including a high-affinity interaction between the Spt6 tandem SH2 domain (Spt6-tSH2) and phosphorylated residues of the Rpb1 subunit in the linker between the catalytic core and the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789061/ https://www.ncbi.nlm.nih.gov/pubmed/34967414 http://dx.doi.org/10.1093/nar/gkab1262 |