Cargando…

The interaction between the Spt6-tSH2 domain and Rpb1 affects multiple functions of RNA Polymerase II

The conserved transcription elongation factor Spt6 makes several contacts with the RNA Polymerase II (RNAPII) complex, including a high-affinity interaction between the Spt6 tandem SH2 domain (Spt6-tSH2) and phosphorylated residues of the Rpb1 subunit in the linker between the catalytic core and the...

Descripción completa

Detalles Bibliográficos
Autores principales: Connell, Zaily, Parnell, Timothy J, McCullough, Laura L, Hill, Christopher P, Formosa, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789061/
https://www.ncbi.nlm.nih.gov/pubmed/34967414
http://dx.doi.org/10.1093/nar/gkab1262