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The interaction between the Spt6-tSH2 domain and Rpb1 affects multiple functions of RNA Polymerase II

The conserved transcription elongation factor Spt6 makes several contacts with the RNA Polymerase II (RNAPII) complex, including a high-affinity interaction between the Spt6 tandem SH2 domain (Spt6-tSH2) and phosphorylated residues of the Rpb1 subunit in the linker between the catalytic core and the...

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Detalles Bibliográficos
Autores principales:	Connell, Zaily, Parnell, Timothy J, McCullough, Laura L, Hill, Christopher P, Formosa, Tim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789061/ https://www.ncbi.nlm.nih.gov/pubmed/34967414 http://dx.doi.org/10.1093/nar/gkab1262

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