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Phylogenetic and Molecular Analyses Identify SNORD116 Targets Involved in the Prader–Willi Syndrome

The eutherian-specific SNORD116 family of repeated box C/D snoRNA genes is suspected to play a major role in the Prader–Willi syndrome (PWS), yet its molecular function remains poorly understood. Here, we combined phylogenetic and molecular analyses to identify candidate RNA targets. Based on the an...

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Detalles Bibliográficos
Autores principales: Baldini, Laeya, Robert, Anne, Charpentier, Bruno, Labialle, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789076/
https://www.ncbi.nlm.nih.gov/pubmed/34893870
http://dx.doi.org/10.1093/molbev/msab348