“Bind, cleave and leave”: multiple turnover catalysis of RNA cleavage by bulge–loop inducing supramolecular conjugates

Antisense sequence-specific knockdown of pathogenic RNA offers opportunities to find new solutions for therapeutic treatments. However, to gain a desired therapeutic effect, the multiple turnover catalysis is critical to inactivate many copies of emerging RNA sequences, which is difficult to achieve...

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Detalles Bibliográficos
Autores principales: Amirloo, Bahareh, Staroseletz, Yaroslav, Yousaf, Sameen, Clarke, David J, Brown, Tom, Aojula, Harmesh, Zenkova, Marina A, Bichenkova, Elena V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789077/
https://www.ncbi.nlm.nih.gov/pubmed/34967410
http://dx.doi.org/10.1093/nar/gkab1273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789077/
https://www.ncbi.nlm.nih.gov/pubmed/34967410
http://dx.doi.org/10.1093/nar/gkab1273

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