Translesion DNA synthesis-driven mutagenesis in very early embryogenesis of fast cleaving embryos

In early embryogenesis of fast cleaving embryos, DNA synthesis is short and surveillance mechanisms preserving genome integrity are inefficient, implying the possible generation of mutations. We have analyzed mutagenesis in Xenopus laevis and Drosophila melanogaster early embryos. We report the occu...

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Detalles Bibliográficos
Autores principales: Lo Furno, Elena, Busseau, Isabelle, Aze, Antoine, Lorenzi, Claudio, Saghira, Cima, Danzi, Matt C, Zuchner, Stephan, Maiorano, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789082/
https://www.ncbi.nlm.nih.gov/pubmed/34939656
http://dx.doi.org/10.1093/nar/gkab1223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789082/
https://www.ncbi.nlm.nih.gov/pubmed/34939656
http://dx.doi.org/10.1093/nar/gkab1223

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