Effect of oseltamivir phosphate versus placebo on platelet recovery and plasma leakage in adults with dengue and thrombocytopenia; a phase 2, multicenter, double-blind, randomized trial

BACKGROUND: Thrombocytopenia, bleeding and plasma leakage are major complications of dengue. Activation of endogenous sialidases with desialylation of platelets and endothelial cells may underlie these complications. We aimed to assess the effects of the neuraminidase inhibitor oseltamivir on platel...

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Detalles Bibliográficos
Autores principales: Tunjungputri, Rahajeng N., Riswari, Silvita Fitri, Pramudo, Setyo G., Kuntjoro, Lydia, Alisjahbana, Bachti, Nugraha, Harry Galuh, van der Ven, Andre, Gasem, Muhammad Hussein, de Mast, Quirijn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789129/
https://www.ncbi.nlm.nih.gov/pubmed/34995275
http://dx.doi.org/10.1371/journal.pntd.0010051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789129/
https://www.ncbi.nlm.nih.gov/pubmed/34995275
http://dx.doi.org/10.1371/journal.pntd.0010051

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