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Short-term oral rapamycin prevents age-related learning impairment in mice

Effective treatments to prevent or delay age-related learning impairment are not generally available. In a preliminary preclinical study, mice 20 months of age were fed a diet containing 14 ppm rapamycin, an inhibitor of mTOR, for three months and then tested in a spatial navigation task. Mice fed t...

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Detalles Bibliográficos
Autores principales: Lei, Haoyi, Wang, Juan, Ladiges, Warren, Jiang, Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789159/
https://www.ncbi.nlm.nih.gov/pubmed/35083446
http://dx.doi.org/10.31491/apt.2020.09.033