ERBB2 Copy Number as a Quantitative Biomarker for Real-World Outcomes to Anti–Human Epidermal Growth Factor Receptor 2 Therapy in Advanced Gastroesophageal Adenocarcinoma

PURPOSE: Human epidermal growth factor receptor 2 (HER2) overexpression or amplification (ERBB2amp) are biomarkers for approved anti-HER2 therapies. ERBB2amp may better predict response compared with immunohistochemistry or in situ hybridization, and quantitative copy number (CN) may further stratif...

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Detalles Bibliográficos
Autores principales: Zhang, Liangliang, Hamdani, Omar, Gjoerup, Ole, Cho-Phan, Cheryl, Snider, Jeremy, Castellanos, Emily, Nimeiri, Halla, Frampton, Garrett, Venstrom, Jeffrey M., Oxnard, Geoffrey, Klempner, Samuel J., Schrock, Alexa B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2022
Materias:
ORIGINAL REPORTS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789214/
https://www.ncbi.nlm.nih.gov/pubmed/35050711
http://dx.doi.org/10.1200/PO.21.00330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789214/
https://www.ncbi.nlm.nih.gov/pubmed/35050711
http://dx.doi.org/10.1200/PO.21.00330

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