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The functional impact of nuclear reorganization in cellular senescence

Cellular senescence is the irreversible cell cycle arrest in response to DNA damage. Because senescent cells accumulate with age and contribute to chronic inflammation, they are promising therapeutic targets for healthspan extension. The senescent phenotype can vary depending on cell type and on the...

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Detalles Bibliográficos
Autores principales: Rocha, Azucena, Dalgarno, Audrey, Neretti, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789270/
https://www.ncbi.nlm.nih.gov/pubmed/33755107
http://dx.doi.org/10.1093/bfgp/elab012