Native proline-rich motifs exploit sequence context to target actin-remodeling Ena/VASP protein ENAH

The human proteome is replete with short linear motifs (SLiMs) of four to six residues that are critical for protein-protein interactions, yet the importance of the sequence surrounding such motifs is underexplored. We devised a proteomic screen to examine the influence of SLiM sequence context on p...

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Detalles Bibliográficos
Autores principales: Hwang, Theresa, Parker, Sara S, Hill, Samantha M, Grant, Robert A, Ilunga, Meucci W, Sivaraman, Venkatesh, Mouneimne, Ghassan, Keating, Amy E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789275/
https://www.ncbi.nlm.nih.gov/pubmed/35076015
http://dx.doi.org/10.7554/eLife.70680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789275/
https://www.ncbi.nlm.nih.gov/pubmed/35076015
http://dx.doi.org/10.7554/eLife.70680

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