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Overexpression screen of interferon-stimulated genes identifies RARRES3 as a restrictor of Toxoplasma gondii infection

Toxoplasma gondii is an important human pathogen infecting an estimated one in three people worldwide. The cytokine interferon gamma (IFNγ) is induced during infection and is critical for restricting T. gondii growth in human cells. Growth restriction is presumed to be due to the induction of interf...

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Detalles Bibliográficos
Autores principales: Rinkenberger, Nicholas, Abrams, Michael E, Matta, Sumit K, Schoggins, John W, Alto, Neal M, Sibley, L David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789288/
https://www.ncbi.nlm.nih.gov/pubmed/34871166
http://dx.doi.org/10.7554/eLife.73137