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Epigenetic alterations in stem cell ageing—a promising target for age-reversing interventions?
Ageing is accompanied by loss of tissue integrity and organismal homeostasis partly due to decline in stem cell function. The age-associated decrease in stem cell abundance and activity is often referred to as stem cell exhaustion and is considered one major hallmark of ageing. Importantly, stem cel...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789308/ https://www.ncbi.nlm.nih.gov/pubmed/33738480 http://dx.doi.org/10.1093/bfgp/elab010 |