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Epigenetic alterations in stem cell ageing—a promising target for age-reversing interventions?

Ageing is accompanied by loss of tissue integrity and organismal homeostasis partly due to decline in stem cell function. The age-associated decrease in stem cell abundance and activity is often referred to as stem cell exhaustion and is considered one major hallmark of ageing. Importantly, stem cel...

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Detalles Bibliográficos
Autores principales: Pouikli, Andromachi, Tessarz, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789308/
https://www.ncbi.nlm.nih.gov/pubmed/33738480
http://dx.doi.org/10.1093/bfgp/elab010