Nedd4-2–dependent Ubiquitination Potentiates the Inhibition of Human NHE3 by Cholera Toxin and Enteropathogenic Escherichia coli

BACKGROUND & AIMS: Diarrhea is one of the most common illnesses and is often caused by bacterial infection. Recently, we have shown that human Na(+)/H(+) exchanger NHE3 (hNHE3), but not non-human NHE3s, interacts with the E3 ubiquitin ligase Nedd4-2. We hypothesize that this property of hNHE3 co...

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Detalles Bibliográficos
Autores principales: Jenkin, Kayte A., Han, Yiran, Lin, Songbai, He, Peijian, Yun, C. Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789535/
https://www.ncbi.nlm.nih.gov/pubmed/34823064
http://dx.doi.org/10.1016/j.jcmgh.2021.11.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789535/
https://www.ncbi.nlm.nih.gov/pubmed/34823064
http://dx.doi.org/10.1016/j.jcmgh.2021.11.006

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