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A novel C-terminal DxRSDxE motif in ceramide synthases involved in dimer formation

Ceramide is a lipid moiety synthesized via the enzymatic activity of ceramide synthases (CerSs), six of which have been identified in mammalian cells, and each of which uses a unique subset of acyl-CoAs for ceramide synthesis. The CerSs are part of a larger gene family, the Tram-Lag-CLN8 domain fami...

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Detalles Bibliográficos
Autores principales: Kim, Jiyoon L., Ben-Dor, Shifra, Rosenfeld-Gur, Eden, Futerman, Anthony H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789539/
https://www.ncbi.nlm.nih.gov/pubmed/34942147
http://dx.doi.org/10.1016/j.jbc.2021.101517