Cargando…

RNA-binding protein RBM28 can translocate from the nucleolus to the nucleoplasm to inhibit the transcriptional activity of p53

RNA-binding protein RBM28 (RBM28), as a nucleolar component of spliceosomal small nuclear ribonucleoproteins, is involved in the nucleolar stress response. Whether and how RBM28 regulates tumor progression remains unclear. Here, we report that RBM28 is frequently overexpressed in various types of ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Xin, Zhou, Liwen, Zhong, Jianliang, Zhong, Li, Zhang, Ruhua, Kang, Tiebang, Wu, Yuanzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789582/
https://www.ncbi.nlm.nih.gov/pubmed/34953860
http://dx.doi.org/10.1016/j.jbc.2021.101524