Biologically stable threose nucleic acid-based probes for real-time microRNA detection and imaging in living cells

We successfully fabricated threose nucleic acid (TNA)-based probes for real-time monitoring of target miRNA levels in cells. Our TNA probe is comprised of a fluorophore-labeled TNA reporter strand by partially hybridizing to a quencher-labeled TNA that is designed to be antisense to a target RNA tra...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Fei, Liu, Ling Sum, Li, Pan, Leung, Hoi Man, Tam, Dick Yan, Lo, Pik Kwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789592/
https://www.ncbi.nlm.nih.gov/pubmed/35116190
http://dx.doi.org/10.1016/j.omtn.2021.12.040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789592/
https://www.ncbi.nlm.nih.gov/pubmed/35116190
http://dx.doi.org/10.1016/j.omtn.2021.12.040

Ejemplares similares