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The effects of ARID1A mutations on colorectal cancer and associations with PD‐L1 expression by stromal cells
BACKGROUND: ARID1A is a component of the SWI/SNF complex, which controls the accessibility of proteins to DNA. ARID1A mutations are frequently observed in colorectal cancers (CRCs) and have been reported to be associated with high mutational burden and tumor PD‐L1 expression in vitro. AIM: To clarif...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789618/ https://www.ncbi.nlm.nih.gov/pubmed/34042312 http://dx.doi.org/10.1002/cnr2.1420 |