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The effects of ARID1A mutations on colorectal cancer and associations with PD‐L1 expression by stromal cells

BACKGROUND: ARID1A is a component of the SWI/SNF complex, which controls the accessibility of proteins to DNA. ARID1A mutations are frequently observed in colorectal cancers (CRCs) and have been reported to be associated with high mutational burden and tumor PD‐L1 expression in vitro. AIM: To clarif...

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Detalles Bibliográficos
Autores principales: Kamori, Tomohiro, Oki, Eiji, Shimada, Yoshifumi, Hu, Qingjiang, Hisamatsu, Yuichi, Ando, Koji, Shimokawa, Mototsugu, Wakai, Toshifumi, Oda, Yoshinao, Mori, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789618/
https://www.ncbi.nlm.nih.gov/pubmed/34042312
http://dx.doi.org/10.1002/cnr2.1420