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DNA Based Vaccine Expressing SARS-CoV-2 Spike-CD40L Fusion Protein Confers Protection Against Challenge in a Syrian Hamster Model

SARS-CoV-2 infections present a tremendous threat to public health. Safe and efficacious vaccines are the most effective means in preventing the infections. A variety of vaccines have demonstrated excellent efficacy and safety around the globe. Yet, development of alternative forms of vaccines remai...

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Detalles Bibliográficos
Autores principales: Tamming, Levi A., Duque, Diana, Tran, Anh, Zhang, Wanyue, Pfeifle, Annabelle, Laryea, Emmanuel, Wu, Jianguo, Raman, Sathya N. Thulasi, Gravel, Caroline, Russell, Marsha S., Hashem, Anwar M., Alsulaiman, Reem M., Alhabbab, Rowa Y., Gao, Jun, Safronetz, David, Cao, Jingxin, Wang, Lisheng, Chen, Wangxue, Johnston, Michael J. W., Sauve, Simon, Rosu-Myles, Michael, Li, Xuguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789660/
https://www.ncbi.nlm.nih.gov/pubmed/35095861
http://dx.doi.org/10.3389/fimmu.2021.785349