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The association of high Vancomycin trough concentration with acute kidney injury during combination therapy of Piperacillin/Tazobactam and Vancomycin

BACKGROUND: Co-administration of Piperacillin/Tazobactam (PIPC/TAZ) and Vancomycin (VCM) as an antibiotic therapy for severe infectious diseases increases the risk of nephrotoxicity. We retrospectively investigated the utility of monitoring VCM trough concentration in early stage of developing acute...

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Detalles Bibliográficos
Autores principales: Saito, Syuichiro, Sugimoto, Takeshi, Takenaka, Kei, Goto, Hideaki, Kumahara, Akira, Watanabe, Rikiya, Sugiyama, Daisuke, Yasutomo, Yoshiro, Takatsuki, Kiyonobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789664/
https://www.ncbi.nlm.nih.gov/pubmed/35111893
http://dx.doi.org/10.1016/j.plabm.2022.e00266