Longitudinal High-Throughput Sequencing of the T-Cell Receptor Repertoire Reveals Dynamic Change and Prognostic Significance of Peripheral Blood TCR Diversity in Metastatic Colorectal Cancer During Chemotherapy

Colorectal cancer (CRC) is a major cause of cancer mortality and morbidity. Despite advances in chemotherapy and targeted therapy, unsustainable clinical benefit was noted due to recurrence and therapy resistance. The immune status of the cancer patient may affect the effectiveness of disease treatm...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yi-Tung, Hsu, Hung-Chih, Lee, Yun-Shien, Liu, Hsuan, Tan, Bertrand Chin-Ming, Chin, Chia-Yin, Chang, Ian Yi-Feng, Yang, Chia-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789675/
https://www.ncbi.nlm.nih.gov/pubmed/35095836
http://dx.doi.org/10.3389/fimmu.2021.743448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789675/
https://www.ncbi.nlm.nih.gov/pubmed/35095836
http://dx.doi.org/10.3389/fimmu.2021.743448

Ejemplares similares