Cargando…

Longitudinal High-Throughput Sequencing of the T-Cell Receptor Repertoire Reveals Dynamic Change and Prognostic Significance of Peripheral Blood TCR Diversity in Metastatic Colorectal Cancer During Chemotherapy

Colorectal cancer (CRC) is a major cause of cancer mortality and morbidity. Despite advances in chemotherapy and targeted therapy, unsustainable clinical benefit was noted due to recurrence and therapy resistance. The immune status of the cancer patient may affect the effectiveness of disease treatm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Yi-Tung, Hsu, Hung-Chih, Lee, Yun-Shien, Liu, Hsuan, Tan, Bertrand Chin-Ming, Chin, Chia-Yin, Chang, Ian Yi-Feng, Yang, Chia-Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789675/ https://www.ncbi.nlm.nih.gov/pubmed/35095836 http://dx.doi.org/10.3389/fimmu.2021.743448

Ejemplares similares

A facile technology for the high-throughput sequencing of the paired VH:VL and TCRβ:TCRα repertoires
por: Tanno, Hidetaka, et al.
Publicado: (2020)

High Throughput Sequencing of T Cell Antigen Receptors Reveals a Conserved TCR Repertoire
por: Hou, Xianliang, et al.
Publicado: (2016)

Profiling of the TCRβ repertoire in non-model species using high-throughput sequencing
por: Migalska, Magdalena, et al.
Publicado: (2018)

Longitudinal high-throughput TCR repertoire profiling reveals the dynamics of T-cell memory formation after mild COVID-19 infection
por: Minervina, Anastasia A, et al.
Publicado: (2021)

Huge Overlap of Individual TCR Beta Repertoires
por: Shugay, Mikhail, et al.
Publicado: (2013)

Human γδ TCR Repertoires in Health and Disease
por: Fichtner, Alina Suzann, et al.
Publicado: (2020)

Machine Learning Approaches to TCR Repertoire Analysis
por: Katayama, Yotaro, et al.
Publicado: (2022)

Globally shared TCR repertoires within the tumor-infiltrating lymphocytes of patients with metastatic gynecologic cancer
por: Kim, Taehoon, et al.
Publicado: (2023)

Characteristics, dynamic changes, and prognostic significance of TCR repertoire profiling in patients with renal cell carcinoma
por: Guo, Liping, et al.
Publicado: (2020)

Characterization of the TCR V repertoire of piperacillin-specific T-cells
por: Al-Attar, Zaid, et al.
Publicado: (2014)

Analysis of the TCR Repertoire in HIV-Exposed but Uninfected Infants
por: Gabriel, Benjamin, et al.
Publicado: (2019)

An innovative and affordable quantitative assessment of human TCR repertoire
por: Amoriello, Roberta, et al.
Publicado: (2020)

Deciphering the TCR Repertoire to Solve the COVID-19 Mystery
por: Gutierrez, Lucas, et al.
Publicado: (2020)

Genetic and environmental determinants of human TCR repertoire diversity
por: Krishna, Chirag, et al.
Publicado: (2020)

Characterization of the TCRβ repertoire of peripheral MR1-restricted MAIT cells in psoriasis vulgaris patients
por: Jirouš Drulak, Maja, et al.
Publicado: (2023)

Germline-Encoded TCR-MHC Contacts Promote TCR V Gene Bias in Umbilical Cord Blood T Cell Repertoire
por: Gao, Kai, et al.
Publicado: (2019)

Characterization of human αβTCR repertoire and discovery of D-D fusion in TCRβ chains
por: Liu, Peipei, et al.
Publicado: (2014)

Determination of the complexity and diversity of the TCR β-chain CDR3 repertoire in bladder cancer using high-throughput sequencing
por: Ma, Jingsheng, et al.
Publicado: (2019)

Composition and diversity analysis of the TCR CDR3 repertoire in patients with idiopathic orbital inflammation using high-throughput sequencing
por: Fang, Yenan, et al.
Publicado: (2023)

Intratumoral Convergence of the TCR Repertoires of Effector and Foxp3(+) CD4(+) T cells
por: Kuczma, Michal, et al.
Publicado: (2010)

Predominant Role of T Cell Receptor (TCR)-α Chain in Forming Preimmune TCR Repertoire Revealed by Clonal TCR Reconstitution System
por: Yokosuka, Tadashi, et al.
Publicado: (2002)

A comprehensive analysis of the germline and expressed TCR repertoire in White Peking duck
por: Yang, Zhi, et al.
Publicado: (2017)

Dynamics of TCR repertoire and T cell function in COVID-19 convalescent individuals
por: Luo, Lingjie, et al.
Publicado: (2021)

A new high-throughput sequencing method for determining diversity and similarity of T cell receptor (TCR) α and β repertoires and identifying potential new invariant TCR α chains
por: Kitaura, Kazutaka, et al.
Publicado: (2016)

Corrigendum: Germline-Encoded TCR-MHC Contacts Promote TCR V Gene Bias in Umbilical Cord Blood T Cell Repertoire
por: Gao, Kai, et al.
Publicado: (2020)

EV-miRome-wide profiling uncovers miR-320c for detecting metastatic colorectal cancer and monitoring the therapeutic response
por: Yang, Chan-Keng, et al.
Publicado: (2022)

A set point in the selection of the αβTCR T cell repertoire imposed by pre-TCR signaling strength
por: Bovolenta, Elena R., et al.
Publicado: (2022)

Activation of the Hedgehog signaling pathway in T-lineage cells inhibits TCR repertoire selection in the thymus and peripheral T-cell activation
por: Rowbotham, Nicola J., et al.
Publicado: (2007)

Characterization of the TCR β Chain Repertoire in Peripheral Blood from Hepatitis B Vaccine Responders and Non-Responders
por: Yang, Jiezuan, et al.
Publicado: (2022)

Skewing of the TCR V repertoire in SMX-NO specific T cell responses
por: Faulkner, Lee, et al.
Publicado: (2014)

Systematic Comparative Evaluation of Methods for Investigating the TCRβ Repertoire
por: Liu, Xiao, et al.
Publicado: (2016)

Accelerated Loss of TCR Repertoire Diversity in Common Variable Immunodeficiency
por: Wong, Gabriel K., et al.
Publicado: (2016)

TCR3d: The T cell receptor structural repertoire database
por: Gowthaman, Ragul, et al.
Publicado: (2019)

Inherent reactivity of unselected TCR repertoires to peptide-MHC molecules
por: Krovi, S. Harsha, et al.
Publicado: (2019)

Distorted TCR repertoires define multisystem inflammatory syndrome in children
por: Malik, Amna, et al.
Publicado: (2022)

TCR repertoire landscape reveals macrophage-mediated clone deletion in endotoxin tolerance
por: Zhao, Juanjuan, et al.
Publicado: (2023)

Monthly tegafur–uracil maintenance for increasing relapse-free survival in ypStage III rectal cancer patients after preoperative radiotherapy, radical resection, and 12 postoperative chemotherapy cycles: a retrospective study
por: Kuo, Yi-Hung, et al.
Publicado: (2019)

The Risk of Peripheral Arterial Disease after Parathyroidectomy in Patients with End-Stage Renal Disease
por: Hsu, Yueh-Han, et al.
Publicado: (2016)

A discrete chromatin loop in the murine Tcra-Tcrd locus shapes the TCRδ and TCRα repertoires
por: Chen, Liang, et al.
Publicado: (2015)

Single-Cell TCR Sequencing Reveals the Dynamics of T Cell Repertoire Profiling During Pneumocystis Infection
por: Yang, Hu-Qin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_5ubpaq8dtr4ke1g6rfkgrg49ob