Tracking Immunoglobulin Repertoire and Transcriptomic Changes in Germinal Center B Cells by Single-Cell Analysis

In response to T-cell-dependent antigens, mature B cells in the secondary lymphoid organs are stimulated to form germinal centers (GCs), which are histological structures deputed to antibody affinity maturation, a process associated with immunoglobulin gene editing by somatic hypermutation (SHM) and...

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Detalles Bibliográficos
Autores principales: Corinaldesi, Clarissa, Holmes, Antony B., Shen, Qiong, Grunstein, Eli, Pasqualucci, Laura, Dalla-Favera, Riccardo, Basso, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789751/
https://www.ncbi.nlm.nih.gov/pubmed/35095922
http://dx.doi.org/10.3389/fimmu.2021.818758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789751/
https://www.ncbi.nlm.nih.gov/pubmed/35095922
http://dx.doi.org/10.3389/fimmu.2021.818758

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