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Colistin exposure enhances expression of eptB in colistin-resistant Escherichia coli co-harboring mcr-1

Colistin resistance has increased due to the increasing and inappropriate use of this antibiotic. The mechanism involves modification of lipid A with phosphoethanolamine (PEtN) and/or 4-amino-4deoxy-l-arabinose (L-Ara4N). EptA and eptB catalyze the transfer of phosphoethanolamine to lipid A. In this...

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Detalles Bibliográficos
Autores principales: Elizabeth, Rajkumari, Baishya, Somorita, Kalita, Bubul, Wangkheimayum, Jayalaxmi, Choudhury, Manabendra Dutta, Chanda, Debadatta Dhar, Bhattacharjee, Amitabha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789769/
https://www.ncbi.nlm.nih.gov/pubmed/35079093
http://dx.doi.org/10.1038/s41598-022-05435-0