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Modular assembly of the principal microtubule nucleator γ-TuRC

The gamma-tubulin ring complex (γ-TuRC) is the principal microtubule nucleation template in vertebrates. Recent cryo-EM reconstructions visualized the intricate quaternary structure of the γ-TuRC, containing more than thirty subunits, raising fundamental questions about γ-TuRC assembly and the role...

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Detalles Bibliográficos
Autores principales: Würtz, Martin, Zupa, Erik, Atorino, Enrico S., Neuner, Annett, Böhler, Anna, Rahadian, Ariani S., Vermeulen, Bram J. A., Tonon, Giulia, Eustermann, Sebastian, Schiebel, Elmar, Pfeffer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789826/
https://www.ncbi.nlm.nih.gov/pubmed/35078983
http://dx.doi.org/10.1038/s41467-022-28079-0