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High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation

Ribosomes are complex and highly conserved ribonucleoprotein assemblies catalyzing protein biosynthesis in every organism. Here we present high-resolution cryo-EM structures of the 80S ribosome from a thermophilic fungus in two rotational states, which due to increased 80S stability provide a number...

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Detalles Bibliográficos
Autores principales: Kišonaitė, Miglė, Wild, Klemens, Lapouge, Karine, Ruppert, Thomas, Sinning, Irmgard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789840/
https://www.ncbi.nlm.nih.gov/pubmed/35079002
http://dx.doi.org/10.1038/s41467-022-27967-9