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Uncovering emergent phenotypes in endothelial cells by clustering of surrogates of cardiovascular risk factors

Endothelial dysfunction (ED) is a hallmark of atherosclerosis and is influenced by well-defined risk factors, including hypoxia, dyslipidemia, inflammation, and oscillatory flow. However, the individual and combined contributions to the molecular underpinnings of ED remain elusive. We used global ge...

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Detalles Bibliográficos
Autores principales: Pinheiro-de-Sousa, Iguaracy, Fonseca-Alaniz, Miriam H., Teixeira, Samantha K., Rodrigues, Mariliza V., Krieger, Jose E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789842/
https://www.ncbi.nlm.nih.gov/pubmed/35079076
http://dx.doi.org/10.1038/s41598-022-05404-7