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Receptor-targeted nanoparticles modulate cannabinoid anticancer activity through delayed cell internalization

Δ(9)-tetrahydrocannabinol (Δ(9)-THC) is known for its antitumor activity and palliative effects. However, its unfavorable physicochemical and biopharmaceutical properties, including low bioavailability, psychotropic side effects and resistance mechanisms associated to dosing make mandatory the devel...

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Detalles Bibliográficos
Autores principales: Durán-Lobato, Matilde, Álvarez-Fuentes, Josefa, Fernández-Arévalo, Mercedes, Martín-Banderas, Lucía
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789857/
https://www.ncbi.nlm.nih.gov/pubmed/35079042
http://dx.doi.org/10.1038/s41598-022-05301-z