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Receptor-targeted nanoparticles modulate cannabinoid anticancer activity through delayed cell internalization
Δ(9)-tetrahydrocannabinol (Δ(9)-THC) is known for its antitumor activity and palliative effects. However, its unfavorable physicochemical and biopharmaceutical properties, including low bioavailability, psychotropic side effects and resistance mechanisms associated to dosing make mandatory the devel...
Autores principales: | Durán-Lobato, Matilde, Álvarez-Fuentes, Josefa, Fernández-Arévalo, Mercedes, Martín-Banderas, Lucía |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789857/ https://www.ncbi.nlm.nih.gov/pubmed/35079042 http://dx.doi.org/10.1038/s41598-022-05301-z |
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