The HeyL-Aromatase Axis Promotes Cancer Stem Cell Properties by Endogenous Estrogen-Induced Autophagy in Castration-Resistant Prostate Cancer

Treatment of patients with castration-resistant prostate cancer (CRPC) remains a major clinical challenge. We previously showed that estrogenic effects contribute to CRPC progression and are primarily caused by the increased endogenous estradiol produced via highly expressed aromatase. However, the...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Qimei, Cao, Jiasong, Du, Xiaoling, Yang, Kuo, Shen, Yongmei, Wang, Weishu, Klocker, Helmut, Shi, Jiandang, Zhang, Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789881/
https://www.ncbi.nlm.nih.gov/pubmed/35096586
http://dx.doi.org/10.3389/fonc.2021.787953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789881/
https://www.ncbi.nlm.nih.gov/pubmed/35096586
http://dx.doi.org/10.3389/fonc.2021.787953

Ejemplares similares