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The HeyL-Aromatase Axis Promotes Cancer Stem Cell Properties by Endogenous Estrogen-Induced Autophagy in Castration-Resistant Prostate Cancer

Treatment of patients with castration-resistant prostate cancer (CRPC) remains a major clinical challenge. We previously showed that estrogenic effects contribute to CRPC progression and are primarily caused by the increased endogenous estradiol produced via highly expressed aromatase. However, the...

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Detalles Bibliográficos
Autores principales:	Lin, Qimei, Cao, Jiasong, Du, Xiaoling, Yang, Kuo, Shen, Yongmei, Wang, Weishu, Klocker, Helmut, Shi, Jiandang, Zhang, Ju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789881/ https://www.ncbi.nlm.nih.gov/pubmed/35096586 http://dx.doi.org/10.3389/fonc.2021.787953

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