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Selective translation of epigenetic modifiers affects the temporal pattern and differentiation of neural stem cells

The cerebral cortex is formed by diverse neurons generated sequentially from neural stem cells (NSCs). A clock mechanism has been suggested to underlie the temporal progression of NSCs, which is mainly defined by the transcriptome and the epigenetic state. However, what drives such a developmental c...

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Detalles Bibliográficos
Autores principales: Wu, Quan, Shichino, Yuichi, Abe, Takaya, Suetsugu, Taeko, Omori, Ayaka, Kiyonari, Hiroshi, Iwasaki, Shintaro, Matsuzaki, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789897/
https://www.ncbi.nlm.nih.gov/pubmed/35078993
http://dx.doi.org/10.1038/s41467-022-28097-y