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Selective translation of epigenetic modifiers affects the temporal pattern and differentiation of neural stem cells
The cerebral cortex is formed by diverse neurons generated sequentially from neural stem cells (NSCs). A clock mechanism has been suggested to underlie the temporal progression of NSCs, which is mainly defined by the transcriptome and the epigenetic state. However, what drives such a developmental c...
Autores principales: | Wu, Quan, Shichino, Yuichi, Abe, Takaya, Suetsugu, Taeko, Omori, Ayaka, Kiyonari, Hiroshi, Iwasaki, Shintaro, Matsuzaki, Fumio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789897/ https://www.ncbi.nlm.nih.gov/pubmed/35078993 http://dx.doi.org/10.1038/s41467-022-28097-y |
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