Cargando…

USP44 regulates irradiation-induced DNA double-strand break repair and suppresses tumorigenesis in nasopharyngeal carcinoma

Radiotherapy is the primary treatment for patients with nasopharyngeal carcinoma (NPC), and approximately 20% of patients experience treatment failure due to tumour radioresistance. However, the exact regulatory mechanism remains poorly understood. Here, we show that the deubiquitinase USP44 is hype...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yang, Zhao, Yin, Yang, Xiaojing, Ren, Xianyue, Huang, Shengyan, Gong, Sha, Tan, Xirong, Li, Junyan, He, Shiwei, Li, Yingqin, Hong, Xiaohong, Li, Qian, Ding, Cong, Fang, Xueliang, Ma, Jun, Liu, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789930/
https://www.ncbi.nlm.nih.gov/pubmed/35079021
http://dx.doi.org/10.1038/s41467-022-28158-2