USP44 regulates irradiation-induced DNA double-strand break repair and suppresses tumorigenesis in nasopharyngeal carcinoma

Radiotherapy is the primary treatment for patients with nasopharyngeal carcinoma (NPC), and approximately 20% of patients experience treatment failure due to tumour radioresistance. However, the exact regulatory mechanism remains poorly understood. Here, we show that the deubiquitinase USP44 is hype...

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Detalles Bibliográficos
Autores principales: Chen, Yang, Zhao, Yin, Yang, Xiaojing, Ren, Xianyue, Huang, Shengyan, Gong, Sha, Tan, Xirong, Li, Junyan, He, Shiwei, Li, Yingqin, Hong, Xiaohong, Li, Qian, Ding, Cong, Fang, Xueliang, Ma, Jun, Liu, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789930/
https://www.ncbi.nlm.nih.gov/pubmed/35079021
http://dx.doi.org/10.1038/s41467-022-28158-2

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