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Electrospun Scaffold Micro-Architecture Induces an Activated Transcriptional Phenotype within Tendon Fibroblasts

Biomaterial augmentation of surgically repaired rotator cuff tendon tears aims to improve the high failure rates (∼40%) of traditional repairs. Biomaterials that can alter cellular phenotypes through the provision of microscale topographical cues are now under development. We aimed to systematically...

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Detalles Bibliográficos
Autores principales: Baldwin, Mathew J., Mimpen, Jolet Y., Cribbs, Adam P., Stace, Edward, Philpott, Martin, Dakin, Stephanie G., Carr, Andrew J., Snelling, Sarah JB.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790033/
https://www.ncbi.nlm.nih.gov/pubmed/35096791
http://dx.doi.org/10.3389/fbioe.2021.795748