Cargando…
Sorting Nexin 27 Enables MTOC and Secretory Machinery Translocation to the Immune Synapse
Sorting nexin 27 (SNX27) association to the retromer complex mediates intracellular trafficking of cargoes containing PSD95/Dlg1/ZO-1 (PDZ)-binding C-terminal sequences from endosomes to the cell surface, preventing their lysosomal degradation. Antigen recognition by T lymphocyte leads to the format...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790036/ https://www.ncbi.nlm.nih.gov/pubmed/35095913 http://dx.doi.org/10.3389/fimmu.2021.814570 |