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Sorting Nexin 27 Enables MTOC and Secretory Machinery Translocation to the Immune Synapse

Sorting nexin 27 (SNX27) association to the retromer complex mediates intracellular trafficking of cargoes containing PSD95/Dlg1/ZO-1 (PDZ)-binding C-terminal sequences from endosomes to the cell surface, preventing their lysosomal degradation. Antigen recognition by T lymphocyte leads to the format...

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Detalles Bibliográficos
Autores principales:	González-Mancha, Natalia, Rodríguez-Rodríguez, Cristina, Alcover, Andrés, Merida, Isabel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790036/ https://www.ncbi.nlm.nih.gov/pubmed/35095913 http://dx.doi.org/10.3389/fimmu.2021.814570

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